Entrepreneurial universities are transforming the traditional role of higher education institutions from centres of teaching to hubs of innovation, research, and thought leadership. (Clark, 1998). These universities not only focus on academic learning but also promote entrepreneurship, innovation, and collaboration with industries and society. The objective of this research is to examine how universities are evolving into entrepreneurial ecosystems and how this transformation contributes to economic development, knowledge creation, and societal impact. The study uses a descriptive research methodology based on secondary data from academic journals, reports, and case studies of leading entrepreneurial universities. The findings indicate that universities that encourage innovation, research commercialization, and industry partnerships tend to produce skilled graduates, startup founders, and innovative solutions to real-world problems. (Etzkowitz & Leydesdorff, 2000). However, challenges such as lack of funding, rigid academic structures, and limited industry interaction still hinder this transformation in many institutions. The study concludes that entrepreneurial universities play a critical role in developing future leaders and innovators by integrating education, research, and entrepreneurship. Strengthening collaboration between academia, industry, and government can further enhance the ability of universities to become global centres of thought leadership. (Jungblut & Lee, 2022).