UV radiation attenuation in a slurry phase reactor as a function of catalyst concentration and pollutant concentration is experimentally measured. It is observed that in most of the practical working ranges of the catalyst concentration as reported by the researchers, the radiation penetration in the remote regions of the reactor is not uniform and not even assured. It is also observed based upon literature review that the optimum parameters generated for slurry phase photo-catalytic reactors by the researchers are highly dependent to the reactor configuration. Here an approach is suggested to generate reactor configuration independent parameters that may be universally applicable.